Bacterial and viral superantigens: roles in autoimmunity?
نویسندگان
چکیده
منابع مشابه
HSP Roles as Biomarkers and Antigens in Bacterial and Viral Infections
Diagnosis of infectious diseases remains an important issue in medical science. Identification of biomarkers can be used to predict early infections. Recently, heat shock proteins (HSPs) have been known as the conserved compounds expressed under stress conditions in both prokaryotic and eukaryotic systems. These proteins act as molecular chaperones. Several studies showed the increased levels o...
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The recent discovery of the mode of interaction between a group of microbial proteins known as superantigens and the immune system has opened a wide area of investigation into the possible role of these molecules in human diseases. Superantigens produced by certain viruses and bacteria, including Mycoplasma species, are either secreted or membrane-bound proteins. A unique feature of these prote...
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Streptococcus pyogenes, also referred to as group A Streptococcus (GAS), is an exclusive human pathogen causing diseases ranging from uncomplicated infections of the throat and skin to severe invasive infections, such as necrotizing fasciitis and streptococcal toxic shock syndrome (STSS). Asymptomatic carriage, particularly in the nasoand oropharyngeal mucosa, is common. GAS is equipped with an...
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in the present study 220 diarrheal samples of children aged between 3-12 months and 100 samples from healthy individuals of the same age group reffered to Shiraz university hospitals were investigated for bacterial and viral agents.Electron microscopy methods were used for the viral investigations,while conventional techniques of bacteriology were used for isolation of bacterial agents.the prev...
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The pyrogenic exotoxins of group A streptococci and staphylococcal enterotoxins are a family of structurally related superantigens with similar biological activity. Two distinct areas have been identified which have a highly conserved amino acid homology in all of the toxin families. A number of peptides were constructed from these regions, some of which were concatenated and polymerized to enh...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1993
ISSN: 0003-4967
DOI: 10.1136/ard.52.suppl_1.s6